GenoSolutions offers one Neurogenomic test:

• Evaluates polymorphisms in genes that modulate methylation, glutathione conjugation, oxidative protection, and the potential to evaluate vascular oxidation.
• Uncovers genetic susceptibility, neurodegenerative disorders, developmental issues, mood disorders, oxidative stress and detoxification capacity

Methylation

MTHFR (methylenetetrahydrofolate reductase)
COMT (catechol-O-methyl transferase)

These genes affect how homocysteine and methionine are metabolized to support formation of S-adenosyl methionine (SAMe). The ability to donate methyl groups affects neurologic function and is modifiable by proper B-vitamin intake.

Detoxification

GSTM (glutathione-s-transferase, M, isoforum)
GSTP (glutathione-s-transferase, P, isoforum)

These genes are responsible for detoxifying products of oxidative stress and carcinogens. Variants decrease detoxification capacity.

Oxidative Protection

SOD-2 (Superoxide dismutase -2)

These genetic variants alter anti-oxidant enzyme activity and modify requirements for anti-oxidants.